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1. Okubo K, Uchida E, Terahara T, Akiyama K, Kobayashi S, Tanaka Y.:Efficacy and safety of emedastine patch, a novel transdermal drug delivery system for allergic rhinitis: Phase III, multicenter, randomized, double-blinded, placebo-controlled, parallel-group comparative study in patients with seasonal allergic rhinitis. Allergol Int. 2018 Jan 29. pii: S1323-8930(17)30189-2. doi: 10.1016/j.alit.2017.12.005.

2. Okubo K, Hashiguchi K, Takeda T, Baba K, Kitagoh H, Miho H, Tomomatsu H, Yamaguchi S, Odani M, Yamamotoya H: A randomized controlled phase II clinical trial comparing ONO-4053, a novel DP1 antagonist, with a leukotriene receptor antagonist pranlukast in patients with seasonal allergic rhinitis. Allergy. 2017 Oct;72(10):1565-1575. doi: 10.1111/all.13174. Epub 2017 May 16.

3. Gotoh M, Kaminuma O, Nakaya A, Katayama K, Watanabe N, Saeki M, Nishimura T, Kitamura N, Okubo K, Hiroi T: Involvement of taste receptors in the effectiveness of sublingual immunotherapy.

4. Allergol Int. 2018 Mar 6. pii: S1323-8930(18)30008-X. doi: 10.1016/j.alit.2018.02.003.

5. Otsuka H, Otsuka K, Matsune S, Okubo K: Assessing the onset of allergic rhinitis by nasal cytology and immunoglobulin E antibody levels in children. Am J Rhinol Allergy. 2018 Jan 1;32(1):16-22. doi: 10.2500/ajra.2018.32.4503.

6. Fujisawa T, Shimoda T, Masuyama K, Okubo K, Honda K, Okano M, Katsunuma T, Urisu A, Kondo Y, Odajima H, Kurihara K, Nagata M, Taniguchi M, Taniuchi S, Doi S, Matsumoto T, Hashimoto S, Tanaka A, Natsui K, Abe N, Ozaki H: Long-term safety of subcutaneous immunotherapy with TO-204 in Japanese patients with house dust mite-induced allergic rhinitis and allergic bronchial asthma: Multicenter, open label clinical trial. Allergol Int. 2017 Dec 7. pii: S1323-8930(17)30165-X. doi: 10.1016/j.alit.2017.11.004.

7. Yonekura S, Okamoto Y, Sakurai D, Okubo K, Gotoh M, Kaneko S, Konnno A: An analysis of factors related to the effect of sublingual immunotherapy on Japanese cedar pollen induced allergic rhinitis. See comment in PubMed Commons belowAllergol Int. 2017 Jul 28. pii: S1323-8930(17)30106-5. doi: 10.1016/j.alit.2017.07.005. [Epub ahead of print]

8. Gotoh M, Kaminuma O, Nakaya A, Katayama K, Motoi Y, Watanabe N, Saeki M, Nishimura T, Kitamura N, Yamaoka K, Okubo K, Hiroi T: Identification of biomarker sets for predicting the efficacy of sublingual immunotherapy against pollen-induced allergic rhinitis. Int Immunol. 2017 Jun 1;29(6):291-300. doi: 10.1093/intimm/dxx034.

9. Okubo K, Masuyama K, Imai T, Okamiya K, Seitzberg D, Konno A: Efficacy and Safety of the SQ house dust mite SLIT-tablet in Japanese adults and adolescents with dust mite-induced allergic rhinitis J Allergy Clin Immunol. 2017 Jun;139(6):1840-1848.e10. doi: 10.1016/j.jaci.2016.09.043. Epub 2016 Nov 15

10. Kanzaki S, Hashiguchi K, Wakabayashi KI, Suematsu K, Okubo K: Histamine antagonist bepotastine suppress nasal symptom cussed by Japanese cedar and cypress pollen exposure. J Drug Asess 2016 Sep 27; 5(1): 15-23.

11. Otsuka H, Tsukagoshi H, Kimura H, Takahashi I, Okubo K: Are respiratory viruses involved in preseasonal symptoms or severity in Japanese cedar pollinosis? Allergy Rhinol (Providence) 2016 Jan; 7(2): 62-8. Doi; 10.2500/ar.2016.7.0157.

12. Bousquet J, Farrell J, Crooks G, Okubo K, et al (256): Scaling up strategy of the chronic respiratory disease programme of the European innovation partnership on active and healthy aging (Actin plan B3: Area 5) Clin Transl Allergy 2016 Jul 29;6:29 doi: 10.1186/s13601-016-0116-9. Review.

13. Miwa M, Hassan S, Miwa M, Okubo K: Filaggrin exists in human nose. Allergol Int 2016 Jul; 65(3): 338-40. Doi: 10.1016/j.alit.2016.01.007.

14. Okubo K, Gotoh M, Togawa M, Saito A, Ohhashi Y (2016) Long-term safety and efficacy of bilastine following up to 12 weeks to 52 weeks of treatment of Japanese patinents with allergic rhinitis: Resluts of an open-label trial. Auris Nasus Larynx http://dx.doi.org/10.1016/j.anl.2016.07.021

15. Okubo K, Inoue H, Numaguchi H, Tanaka K, Saito I, OshimaN, Matsumoto Y, Prohn M, Mehta A, Nishida C, Philip G (2016) Montelukast in the treatment of perennial allergic rhinitis in pediatric Japanese patients; an open-label clinical trial, J Drug Assess http://dx.doi.org/10.1080/21556660.2016.1209507

16. Okubo K, Gotoh M, Asako M, Nomura Y, Togawa M, Saito A, Honda T, Ohnashi Y (2016) Efficacy and safety of birastine in Japanese patients with perennial allergic rhinitis: A muti-center, randomized, double-blind, placebo-controlled, parallel-group phase III study. Allergology Int the CC BY-NC-ND license http://creativecommons.org/licenses/by-nc-nd/4.0/.

17. Mochizuki M, Minowa F, Ishimoto C, Gin A, Ishioka K, Okubo K (2016) The effect of aging biochemical markers in equine serum. J Equine Veterinary Sci 42:1-6. Doi.org/10.1016/j.jevs.2016.03.011

18. Hashiguchi K, Wakabayashi K, Togawa M, Saito A, Okubo, K (2016) Therapeutic effect of bilastine in Japanese cedar pollinosis using an artificial exposure chamber (OHIO chamber). Allergology Int doi.org 10.1016/j.alit.2016.06.009

19. Otsuka H, Takanashi I, Tokunou S, Endo S, Okubo K (2016) Involvemnet of Stahylococcus aureus and Moraxella catarrhalis in Japanese cedar pollionosis. Am J Rhinol Allergy 30: 99-106, doi:10.2500/ajra.2016.30.4283

20. Murakami R, Nakagawa Y, Shimizu M, Wakabayashi A, Negishi Y, Hiroi T, Okubo K, Takahashi H (2016) Effects of Dendritic Cell Subset Manipulation on Airway Allergy in a Mouse Model.Int Arch Allergy Immunol. 2015;168(4):219-32. doi: 10.1159/000443237. Epub 2016 Feb 9.

21. Yonekura S, Okamoto Y, Sakurai D, Sakurai T, Iinuma T, Yamamoto H, Hanazawa T, Horiguchi S, Kurono Y, Honda K, Majima Y, Masuyama K, Takeda N, Fujieda S, Okano M, Ogino S, Okubo K: Complementary and alternative medicine for allergic rhinitis in Japan. Allergol Int. 2017 Jul;66(3):425-431. doi: 10.1016/j.alit.2016.10.006. Epub 2016 Nov 21.

22. Okubo K, Ichimura I, Koyama T, Susuta Y, Izaki H (2015) Double-blind placebo-controlled study of bepotastine besilate in pediatric patients with perennial allergic rhinitis. Expert Opin Pharmacother2015; 16(16): 2395-408. Doi: 10.1517/14656566.2015. 1085511.

23. Bousquet J, Schunemann HJ, Fonseca J, Okubo K, et al(283): MACVIA-ARIA sentinel network for allergic rhinitis (MASK-rhinitis): the new generation guideline implementation. Allergy 2015 Nov; 70(11): 1372-92. Doi 10.111/all.12686. Review

24. Okamoto Y, Okubo K, Yonekura S, Hashiguchi K, Goto M, Otsuka T, Murata T, Nakao Y, Kanazawa C, Nagakura H, Okawa T, Nakano K, Hisamitsu M, Kaneko S, Konno A(2015) Efficacy and safety of sublingual immunotherapy for two seasons in patients with Japanese cedar pollinosis. Int Arch Allergy Immunol 166(4): 177-188

25. Takai T, Okamoto Y, Okubo K, Nagata M, Sakaguch M, Fukutomi Y, Saito A, Yasuueda H, Masuyama K: Japanese Society of Allergology task force report on standardization of house dust mite allergen vaccines-secondary publication. Allergol Int 2015 apr 64(2): 1816 doi 10.1016/j.alit2015.01.005.

26. Okubo K, Okamasa A, Honma G, Komatubara M(2015) Safety and efficacy of fuluticosone furorate nasal spray in Japanese children 2 to <15 years of age with perennial allergic rhinitis: A mutisentre, open-label trial. Allergol Int 64(1)Jan: 60-65.

27. Okubo K, Okamasa A, Honma G, Komatubara M(2014) Efficacy and safety of fuluticosone furorate nasal spray in Japanese children with perennial allergic rhinitis: a mutisentre, randomized, double-blind, placebo-contorolled trial. Allergol Int 63(4)Dec: 543-551.

28. Hosoya K, Masuno S, Hashiguchi K, Okubo K (2014) Placebo-controlled study with OHIO chamber of prophylactic puranlukast for children with Japanese cedar pollinosis: TOPIC-J III study. J Drug Assessment 3: 51-59.

29. Hashiguchi K, Kanzaki S, Wakabayashi K, Tanaka N, Kawashima K, Suematsu K, Tokunaga S, Ogawa K, Okubo K(2013) Efficacy of fuluticasone furoate nasal spray and levocetirizine in patients with Jpanese cadar pollinosis subjected to an artificial exposure chamber. J Drug Assessment 2: 94-105.

30. Sashihara T, Nagata M, Mori T, Gotoh M, Okubo K, Uchida M, Itoh H(2013) Effect of Lactobacillus gasseri OLL2809 and alfa-lactalbumin on university-student athletes: a randomized, double blind, placebo-controlled clinical trial. Appl Physiol Nutr Metab 38: 1228-1235.

31. Higaki T, Okano M, Kariya S, Fujiwara T, Haruna T, Hirai H, Murai A, Gothoh M, Okubo K, Yonekura S, Okamoto Y, Nishizaki K(2013) Determining Minimal Clinically Important Differences in Japanese Cedar/Cypress Pollinosis Patients. Allergology Int 62(4):487-93.

32. Gotoh M, Yuta A, Ohta N, Matsubara A, Okubo K (2013) Severity Assessment of Japanese Cedar Pollinosis Using the Practical Guideline for the Management of Allergic Rhinitis in Japan and the Allergic Rhinitis and its Impact on Asthma Guideline. Allergology Int 62(2): 181-189.

33. Gotoh M, Okubo K, Hashiguchi K, Wakabayashi K, Kanzaki S, Tanaka N, Fujioka M, Kawashima K, Suematsu K, Sasaki K, Iwasaki M, Yamamotoya H(2013) Noninvasive biological evaluation of response to pranlukast treatment in pediatric patients with Japanese cedar pollinosis. Allergy Asthma Proc. 33(6): 459-466.

34. Ohashi R, Wakayama N, kawamoto M, Tsuchiya S, Okubo K (2013) Solitary nasal schwannoma: Usefulness of CD34 and calretinin staining for distinction from histological mimics. J Nippon Med Sch 80(4): 300-306.

35. Fujikura T, Ishida M, Sekine K, Aoki H, Okubo K (2012) Solitary Fibrous Tumor Arising from the Superior Nasal Turbinate: A Case Report. J Nippon Med Sch 79(5): 373-376.

36. Ishida A, Ohta K, Suzuki Y, Kakehata S, Okubo K, Ikeda H, Shiraishi H, Izuhara K (2012) Expression of pendrin and periostin in allergic rhinitis and chronic rhinosinusitis. Allergology Int 61 (4Dec): 589-595.

37. Kamio T, Watanabe K, Okubo K (2012) Acoustic stimulation promotes DNA fragmentation in the guinea pig cochlea. J Nippon Med Sch 79(5): 349-356.

38. Bousquet J, Schnemann HJ, Samolinski B, et al 162/226 in collaboration with the World Health Organization Collaborating center for Asthma and Rhinitis(2012) Allergic rhinitis and its impact on asthma (ARIA): Achievements in 10 years and future needs. J Allergy Clin Immunol 130(5): 1049-1062.

39. Hashiguchi K, Okubo K, Wakabayashi K, Tanaka N, Watada Y, Suematsu K, Gotoh M (2012) The assessment of the optimal duration of early intervention with montelukast in the treatment of Japanese cedar pollinosis symptom induced in an artificial exposure chamber. J Drug Assessment 1: 40-47.

40. Endo S, Gotoh M, Okubo K, Hashiguchi K, Suzuki H, Masuyama K (2012) Trial of pranlukast inhibitory effect for cedar exposure using an OHIO chamber. J Drug Assessment 1: 48-54.

41. Mori S, Pawankar R, Ozu C, Nonaka M, Yagi T, Okubo K (2012) Expression and role of MMP-2, MMp-9, MMP-13, TIMP-1 and TIMP-2 in allergic nasal mucosa. Allergy Asthma Immunol Res 4(4):231-239.

42. Shiiba K, Shindo S, Ikesono T, Sekine K, Matsumura T, Sekiguchi S, Yagi T, Okubo K (2012) Cochlin expression in the rat perilymph during postnatal development. Acta Oto-Laryngologica 132(11):1134-9.

43. Igarashi T, Nakazato Y, Kunishige T, Fujita M, Yamada Y, Fujimoto C, Okubo K, Takanhashi H (2012) Mometasone furorate nasal spray releaves the ocular symptoms of seasonal allergic rhinoconjunctivitis. J Nippon Med Sch 79(3): 182-189.

44. Inai S, Watanabe K, Okubo K (2012)Iducible nitric oxide synthase in cochlear damage after acoustic stimulation in Guinea pigs. J Nippon Med Sch 79(2): 121-128.

45. Wakabayashi K, Hashiguchi K, Kanzaki S, Fujioka M, Tanaka N, Kawashima K, Suematsu K, Yamamotoya H, Iwasaki M, Gotoh M, Horibe S, Naito K, Okubo K (2012) Puranlukast dry syrup inhibits symptoms of Japanese cedar pollinosis in children using OHIO chamber. Allergy Asthma Proc 33(1): 102-109.

46. Yokoshima K, Nakamizo M, Sakanushi A, Ozu R, Yamaguchi S, Tone Y, Inai S, Murakami R, Okubo K (2011) Surgical management of tongue cancer during pregnancy. Auris Nasus Larynx 39(4): 428-430.

47. Kimura S, Pawankar R, Mori S, Nonaka M, Masuno S, Yagi T, Okubo K (2011) Increased expression and role of thymus stromal lymphopoietin in nasal polyposis. Allergy Asthma Immunol Res 3(3): 186-193.

48. Gotoh M, Suzuki H, Okubo K (2011) Delay of onset of symptoms of Japanese cedar pollinosis by treatment with a leukotriene receptor antagonist. Allergol Int 60: 483-489.

49. Ikesono T, Shindo S, sekine K, Shiiba K, Matsuda H, Kusama K, Koizumi Y, Sugizaki K, Sekiguchi S, Kataoka R, Pawankar R, Baba S, Yagi T, Okubo K (2011) Cochlin-tomoprotein (CTP) detection test identifies traumatic perilynphatic fistula due to penetrating middle ear injury. Acta Otolaryngol 131(9): 937-944.

50. Yonekura S, Okamoto Y, Yamasaki K, Horiguchi S, Hanazawa T, Matsune S, Kurono Y, Yamada T, Fujieda S, Okano M, Okubo K (2011) A randomized double-blind, placebo-controlled study of Ten-Cha (Rubus suavissimus) on house dust mite allergic rhinitis. Auris Nasus Larynx 38: 600-607.

51. Fujikura T, Okubo K (2011) Adrenomedulin level in the nasal discharge from allergic rhinitis cohort. Peptide 32: 368-373.

52. Yamanaka K, Yuta A, Kakeda M, Kitagawa H, Ogihara H, Gabazza EC, Okubo K, Kurokawa I, Takeuchi K, Mizutani K (2011) SLIT improves cedar pollinosis by restoring IL-10 production form Tr1 and monocyte -IL-10 productivity is critical for becoming allergic- Allergol Int 60: 45-51.

53. Gotoh M, Hashiguchi K, Okubo K (2011) Efficacy of epinastine hydrochloride for antigen-provoked nasal symptoms in subjects with orchard grass pollinosis. Allergol Int 60(1): 69-77.

54. Nishihata S, Murata T, Inose K, Okubo K, Sahashi N, Takahashi H, Hirooka J, Hoshiyama Y, Murayama K, Mezawa A, Yokoyama T, Endo T, Saiga T, Saito Y (2010) Prevalence of Japanese cedar pollinosis in Tokyo: a survey conducted by the Tokyo Metropolitan Government. Clin Exp Allergy Rev 10(8): 8-11.

55. Okubo K, Okuda M, Magara H, Kaneko K (2010) Olopatadine hydrochloride in children: efficacy and safety for perennial allergic rhinitis. Curr Med Res Opin 26(7): 1657-1665.

56. Makino Y, Noguchi E, Takahashi N, Mastumoto Y, Kubo S, Yamada T, Imoto Y, Ito Y, Osawa Y, Shibasaki M, Uchida K, Meno K, Suzuki H, Okubo K, Arinami T, Fujieda S (2010) Apolipoprotein A-IV is a candidate target molecule for the treatment of seasonal allergic rhinitis. J Allergy Clin Immunol 126(6): 1163-1169, e5.

57. Gotoh M, Okubo K, Okuda M, Hamada C (2010) Clinical pharmacology study of the corticosteroid nasal spray dexamethasone cipecilate (NS-126): examination of the efficacy in the nasal induction test. Expert Opin Investig Drugs. 19: 1475-1486.

58. Okubo K, Uchida E, Nogami S (2010) Levocabastine nasal spray significantly improves perennial allergic rhinitis: A single blind placebo-controlled study. Auris Nasus Larynx 37: 436-442.

59. Okubo K, Nakashima M, Miyake N, Komatsubara M, Okuda M. (2009) Comparison of fluticasone furoate and fluticasone propionate for the treatment of Japanese cedar pollinosis. Allergy Asthma Proc. 30:84-94.

60. Ogino S, Nagakura T, Okubo K, Sato N, Takahashi M, Ishikawa T. (2009) Re-treatment with omalizumab at one year interval for Japanese cedar pollen-induced seasonal allergic rhinitis is effective and well tolerated. Int Arch Allergy Immunol 149:239-245.

61. Sasaki K, Okamoto Y, Yonekura S, Okawa T, Horiguchi S, Chazono H, Hisamitsu, Sakurai D, Hanazawa T, Okubo K. (2009) Cedar and cypress pollinosis and allergic rhinitis: Quality of life effects of early intervention with leukotriene receptor antagonists. Int Arch Allergy Immunol 149: 350-358.

62. Hashiguchi K, Tang H, Fujita T, Suematsu K, Tsubaki S, Nagakura H, Kitajima S, Gotoh M, Okubo K (2009) Validation study of the OHIO chamber in patients with Japanese Cedar pollinosis. Int Arch Allergy Immunol 149:141-149.

63. Hashiguchi K, Tang H, Fujita T, Suematsu K, Gotoh M, Okubo K. (2009) Bepotastine besilate OD tablets suppress nasal symptoms caused by Japanese cedar pollen exposure in an artificial exposure chamber (OHIO Chamber). Expert Opin Pharmacother 10: 523-9.

64. Gotoh M, Sashihara T, Ikegami S, Yamaji T, Kino K, Orii N, Taketomo N, Okubo K. (2009) Efficacy of Oral Administration of a Heat-Killed Lactobacillus gasseri OLL2809 on Patients of Japanese Cedar Pollinosis with High Japanese-Cedar Pollen-Specific IgE. Biosci Biotechnol Biochem 73: 90144-1-7.

65. Yonekura S, Okamoto Y, Okubo K, Okawa T, Gotoh M, Suzuki H, Kakuma T, Horiguchi S, Hanazawa T, Konno A, Okuda M. (2009) Beneficial effects of leukotriene receptor antagonists in the prevention of cedar pollinosis in a community setting. J Investig Allergol Clin. Immunol 19:195-200.

66. Yamanaka KI, Yuta A, Kakeda M, Sasaki R, Kitagawa H, Gabazza EC, Okubo K, Kurokawa I, Mizutani H. (2009) Induction of IL-10-producing regulatory T cells with TCR diversity by epitope-specific immunotherapy in pollinosis. J Allergy Clin Immunol 124:842-845.

67. Okubo K, Baba K (2008) Therapeutic effect of montelukast, a cysteinyl leukotriene receptor 1 antagonist, on Japanese patients with seasonal allergic rhinitis. Allergol Int 57: 247-255.

68. Okubo K, Gotoh M, Fujieda S, Okano M, Yoshida H, Morikawa H, Masuyama K, Okamoto Y, Kobayashi M (2008) A randomized double-blind comparative study of sublingual immunotherapy for cedar pollinosis. Allergol Int 57: 265-275.

69. Okubo K, Nakashima M, Miyake N, Komatsubara M, Okuda M. (2008) Dose-ranging study of fluticasone furoate nasal spray for Japanese patients with perennial allergic rhinitis. Curr Med Res Opin 24: 3393-3403.

70. Sakashita M, Yasuda1 K, Hirota T, Harada M, Ohkubo K, Osawa Y, Fujieda S, Nakamura S, Nakanishi K, YoshimotoT, Tamari M. (2008) Association of serum IL-33 level and the IL-33 genetic variant with Japanese cedar pollinosis. Clin Exp Allergy 38: 181875-1881.

71. Okano M, Otsuki N, Azuma M, Fujiwara T, Kariya S, Sugata Y, Higaki T, Kino K, Tanimoto Y, Okubo K, Nishizaki K (2008) Allergen-specific immunotherapy alters the expression of BTLA, a co-inhibitory molecule, in allergic rhinitis. Clin Exp Allergy 38: 1891-1900.

72. Sashihara T, Ikegami S, Sueki N, Yamaji T, Kino K, Takemoto N, Gotoh M, Okubo K (2008) Oral administration of heat-killed Lactobacillus gasseri OLL2809 reduces cedar pollen antigen-induced peritoneal eosinophilia in mice. Allergol Int 57: 397-403.

73. Okubo K, Baba K (2008) A double-blind non-inferiority clinical study of montelukast, acysteinyl leukotriene receptor antagonist, compared with Pranlukast in patients with seasonal allergic rhinitis. Allergol Int 57: 383-390.

74. Komatsu N, Harada M, Nakagawa M, Tanaka Y, Ono T, Gohara S, Ohkubo K, Itoh K. (2008) A correlation between symptom severity and unbalanced reactive IgA production in Japanese cedar pollinosis patients. Asian Pac J Allergy Immunol 26:97-104.

75. Hashiguchi K, Tang H, Fujita T, Tsubaki S, Fujita M, Suematsu K, Gotoh M, Okubo K. (2007) Preliminary study on Japanese cedar pollinosis in an artificial exposure chamber (OHIO chamber). Allergol Int 56: 125-130.

76. Nagakura T, Ogino S, Okubo K, Sato N, Takahashi M, Ishikawa T. (2007) Omalizumab is more effective than suplatast tosilate in the treatment of Japanese cedar pollen-induced seasonal allergic rhinitis. Clin Exp Allergy 38: 329-337.

77. Okubo K, Gotoh M. (2006) Inhibition of the antigen provoked nasal reaction by second-generation antihistamines in patients with Japanese cedar pollinosis. Allergology International 55: 261-269.

78. Okubo K, Ogino S, Nagakura T, Ishikawa T. (2006) Omalizumab is effective and safe in the treatment of Japanese cedar pollen-induced seasonal allergic rhinitis. Allergol Int 55: 379-386.

79. Okubo K, Gotoh M, Shimada K, Ristu M, Okuda M, Crawford B. (2005) Fexofenadine improves the quality of life and work productivity in Japanese patients with seasonal allergic rhinitis during the peak cedar pollinosis season. Int Arch Allergy Immunol 136: 148-154.

80. Gotoh M, Okubo K. (2005) Sublingual immunotherapy for Japanese cedar pollinosis. Allergol Int 54: 167-171.

81. Okuda M, Ohkubo K, Goto M, Okamoto Y, Konno A, Baba K, Ogino S, Enomoto M, Imai T, So N, Ishikawa Y, Takenaka Y, Manndai T, Crawford B. (2005) Comparative study of two Japanese rhinoconjunctivitis quality-of-life questionnaires. Acta Oto-Laryngologica 125: 10. 736-744.

82. Gotoh M, Okubo K, Okuda M. (2005) Inhibitory effects of facemasks and eyeglasses on invasion of pollen particles in the nose and eye: clinical study. Rhinology 43: 266-270.

83. Okuda M, Ohkubo K, Gotoh M, Hiroshima K, Ishida Y, Hori K. (2005) Dynamics of airborne pollen particles from inhalation to allergic reaction in the nose. Rhinology 43: 29-33.

84. Okubo k, Gotoh, Okuda M. (2004) Prevalence of Japanese cedar pollinosis in children aged under 15 years throughout Japan. Clin Exp Allergy Rev 4:31-34, 2004.

85. Okubo K, Gotoh M, Shimada K, Ritsu M, Kobayashi M, Okuda M. (2004) Effect of fexofenadine on the quality of life of Japanese cedar pollinosis patients. Allergol Int 53: 245-254.

86. Ohkubo K, Gotoh M. (2003) Effect of ramatroban, a thromboxane A2 antagonist, in the treatment of perennial allergic rhinitis. Allergology International 52: 131-138.

87. Gotoh M, Okubo K, Okuda M. (2003) Repeated antigen challenge in patients with perennial allergic rhinitis to house dust mite. Allergol Int 52: 207-212.

88. Okubo K, Pawankar R, Gotoh M, Yagi T. (1999) Adhesive explant culture of allergic nasal mucosa: Effect of emedastine difumarate, an anti-allergic drug. Jpn J Pharmacol 79: 351-356.

89. Okubo K, Okuda M. (1998) Time-course changes in nasal airway resistance after house dust antigen challenge: With special reference to late phase response. Allergol Int 47: 225-232.

90. Ohkubo K, Baraniuk JN, Hohman R, Merida M, Hersh LB, Kaliner MA. (1998) Aminopeptidase activity in human nasal mucosa. J. Allergy Clin. Immunol .102: 741-750.

91. Ohkubo K, Ikeda M, Pawankar R, Gotoh M, Yagi T, Okuda M. (1998) Mechanisms of IL-6, IL-8, and GM-CSF release in nasal secretions of allergic patients after nasal challenge. Rhinology 36; 156-161.

92. Nakamizo M, Pawankar R, Ohkubo K. (1998) Presence of endothelin-1 inhuman salivary glands and tumors. J Nippon Med Sch 65; 471-477.

93. Moss RB, Nagata H, Goff J, Okubo K, Hausfeld J, Kaliner MA. (1997) Constitutive mRNA and immunoreactivity for IL-2 in human nasal mucosa. Clin Exp Allergy 27: 406-412.

94. Baraniuk JN, Ohkubo K, Kwon OJ, Mak J, Davies R, Twort C, Kaliner MA, Letarte M Barnes PJ (1995) Localization of neutral endopeptidase (NEP) in human bronchi. Eur Respir J 8: 1458-1464.

95. Yokoshima K, Ohnishi M, Takizawa R, Okubo K, Yagi T, Okuda M. (1995) Distribution of mast cells in inverted papilloma and squamous cell carcinoma of the nose. Am J Rhinol 9: 57-62.

96. Pawankar RU, Okuda M, Hasegawa S, Suzuki K, Yssel H, Okubo K, Okumura K, Ra C. (1995) Interleukin-13 expression in the nasal mucosa of perennial allergic rhinitis. Am J Respir Crit Care Med 152: 2059-2067.

97. Ohkubo K, Baraniuk JN, Merida M, Hausfeld H, Okada H, Kaliner MA. (1995) Human nasal mucosal carboxypepetidase: Activity, location, and release. J Allergy Clin Immunol 96: 924-931.

98. Ohkubo K. (1994) Cytokine in nasal surface and nasal secretion. Am J Rhinol (suppl) 8: 282-284.

99. Xiao SF, Okuda M, Ohnishi M, Ohkubo K (1994) Specific IgA and IgG antibodies to house dust mite dermatophagoides farinae in nasal secretion. Arerugi 43: 634-644.

100.Ohkubo K, Lee CH, Baraniuk JN, Merida M, Hausfeld JN, Kaliner MA. (1994) Angiotensin -converting enzyme in the human nasal mucosa. Am J Respir Cell Mol Biol 11: 173-180.

101.Ohkubo K, Okuda M, Kaliner MA. (1994) Immunological localization of neuropeptide-degrading enzymes in nasal mucosa. Rhinology 32: 130-133.

102.Mullol J, Chowdhury BA, White MV, Ohkubo K, Rieves RD, Baraniuk J, Hausfeld JN, Shelhamer JH, Kaliner MA. (1993) Endothelin in human nasal mucosa. Am J Respir Cell Mol Biol 8: 393-492.

103.Ohkubo K, Hohman R, Kaulbach H, Hausfeld J, Merida M, Kaliner MA. (1993) Human nasal mucosa neutral endopeptidase; location, quantification, and release. Am J Respir Cell Mol Biol 9: 557-567.

104.Otsuka H, Ohkubo K, Seki H, Ohnishi M, Fujikura T (1993) Mast cell quantitation in nasal polyp, sinus mucosa and nasal turbinate mucosa. J Laryngol Otol 107: 418-422.

105.Baraniuk JN, Ohkubo K, Kwon OJ, Mak J, Rohde J, Kaliner MA, Durham SR, Barnes PJ. (1993) Identification of neutral endopeptidase mRNA in human nasal mucosa. J Appl Physiol 74: 272-279.

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